The Institute for Health Innovation’s Healthy Nevada Project in Reno, NV is searching for Postdoctoral fellows specializing in Human Genetics to join the research team located at the Desert Research Institute in Reno, Nevada. The Healthy Nevada Project focuses on finding associations between an extensive Electronic Medical Record database and a growing population of sequenced participants using the Helix Exome+ platform. There are two open positions broadly focused on: 1) examining relationships between genotype and phenotype in the Healthy Nevada population; 2) identifying Gene X Environment interactions as part of a newly funded NIH R01 project to examine genetic effects and environmental carcinogens with cancer.
Successful candidates will use and develop statistical genetics tools and develop techniques to examine human genotypes and phenotypes to generate focused hypotheses driving the identification of disease targets. The postdoctoral fellows will collaborate with a team of computational molecular biologists and clinical data scientists, clinicians and physicians to study medical and sequencing data to uncover links to and regulation of diseases relevant to Northern Nevada.
This position will be responsible for supporting high-level genomics and phenomics research and publications. Ph.D. degree required.
Ph.D. in bioinformatics, molecular biology, biochemistry, computer science, or related fields.
Minimum three years of experience with genomic data or electronic medical data required.
Proven research experience, publication records
Genetics/genomics data analysis: GWAS, Whole Genome/Exome Studies, WGES, PheWAS
Knowledge and experience with gene-collapsing methods
Strong R programming skills
Well-versed in Unix/Linux environments and shell scripting
Experience using bioinformatics tools and databases: PLINK, PSEQ, IMPUTE2, BEAGLE, UCSC Genome Browser, dbSNP, UK Biobank
Python and/or Perl experience
Strong statistical foundation
Excellent communication skills
Self-motivated and ability to educate themselves independently
Able to work fluidly in a multi-disciplinary team
About Desert Research Institute
The Desert Research Institute (DRI) is a recognized world leader in investigating the effects of natural and human-induced environmental change and advancing technologies aimed at assessing a changing planet. For almost 60 years DRI research faculty, students, and staff have applied scientific understanding to support the effective management of natural resources while meeting Nevada's needs for economic diversification and science-based educational opportunities. With more than 400 employees and two main campuses in Reno and Las Vegas, DRI serves as the non-profit environmental research arm of the Nevada System of Higher Education. In 2016, through its Applied Innovation Center, DRI moved into the Public Health space through its development and support of the Healthy Nevada Project.
Since launching on September 15, 2016, the Healthy Nevada Project has become the largest community-based population health study in the world. Ultimately, the project aspires to offer no-cost genetic testing to any Nevadan interested in learning more about their health and genetic risks while serving as a model for other communities across the country. By better understanding how genetics, environme...nt, social factors and healthcare interact we can help predict who may be at greater risk – allowing for quicker diagnoses and the development of more precise treatment.
Today, DRI researchers and health data scientists are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems, while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. www.healthynv.org